Beyond appetite, tirzepatide improves insulin sensitivity
Tirzepatide belongs to a class of drugs called GLP-1 receptor agonists, which work by mimicking the action of the hormone GLP-1 (glucagon-like peptide-1) to stimulate insulin secretion, suppress glucagon secretion (which helps lower blood sugar levels), and delay gastric emptying
During the catabolism of fatty acids with an odd number of carbon atoms and the amino acids valine, isoleucine, methionine, and threonine, the resultant propionyl-CoA is converted to succinyl-CoA for oxidation in the TCA cycle
These signs, while rare, warrant professional evaluation
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